STATE SHIFTER™ / SENSAI: AI-Enhanced Multisensory Digital Therapeutic for Stress & Anxiety

An adaptive, AI-powered sensory reality system that guides users from high stress and emotional distress toward calm and balance in a single 12-minute session.

57%
Substantial Improvement
1-2
Treatment Sessions
5/7
Improved Quality of Life
State Shifter System Architecture
PROJECT OVERVIEW

What is STATE SHIFTER™ / SENSAI?

STATE SHIFTER™ is an AI-enhanced, multisensory digital therapeutic running on the Sensory Reality Pod (SRP) – a cabin that controls light, sound, scent, temperature, airflow and vibration across 59 actuators to guide users from emotional distress to calm in a single 12-minute protocol.

Clinical Goal

Deliver a brief, evidence-based intervention for stress, anxiety and trauma-related complaints that can be deployed in healthcare, education and high-pressure workplaces.

Hardware Platform

Built on the already commercial Sensory Reality Pod (SRP) with 59 individually addressable actuators for light, sound, scent, airflow, vibration and temperature – validated in daily clinical and corporate use.

AI Innovation

A three-tier AI layer – Static AI, Interactive AI and Adaptive AI – coordinates safe session planning, conversational guidance and real-time bio-feedback adjustment with ≤ 800 ms closed-loop latency.

IMPACT & CONTEXT

Addressing Stress at Scale

In the Netherlands alone, 1.3 million workers per year report stress-related complaints, costing €3.1 billion in absenteeism. STATE SHIFTER™ contributes directly to the KIA Health & Care mission of +5 healthy life years and 30% reduction in health inequality.

  • 1.3 million workers annually affected by stress-related complaints (TNO 2024).
  • €3.1 billion yearly cost in absenteeism due to stress and burnout.
  • Targets KIA Health & Care and AIC4NL missions for healthier, more resilient citizens and workers.

Health & Care

Adaptive stress reduction and anxiety management for patients and high-risk populations, reducing pressure on overstretched mental healthcare services.

Education

Exam-anxiety and focus pods for students, offering quick resets before high-stakes tests or demanding study periods.

Smart Industry

“Mental reset cabins” for shift workers and high-cognitive-load environments, integrated into workplace wellbeing programs.

TECHNICAL INNOVATION

How the AI System Works

STATE SHIFTER™ introduces an adaptive AI engine on top of a mature multisensory hardware platform, creating the first commercial closed-loop system across all five senses.

Core Specifications (Target 2026)

  • Closed-loop latency: ≤ 800 ms from biosensors → AI decision → actuator update.
  • Emotion model: 4-class valence–arousal space (high/low valence × high/low arousal).
  • Classification accuracy: 78–82% on real in-pod data.
  • Adaptive engine: hierarchical policy combining static templates, rule-based safety layer and contextual bandit optimisation.
  • Safety bounds: all actuator changes limited to ±30% of clinically pre-validated static templates.
  • Fail-safe mode: automatic fallback to deterministic sessions when model confidence is low.

Current Prototype Outcomes (n = 410 sessions, 2024–2025)

  • 29% average reduction in perceived stress (STAI-6) after one session.
  • +24% average increase in HRV (rMSSD), indicating improved autonomic balance.
  • +3.1 point increase on 0–10 calmness VAS.
  • Median 7.8 minutes to reach a predefined “calm zone” based on HRV and GSR thresholds.

SENSAI Architecture: Four Modules

Static AI

Generates a safe 12-minute baseline session (720 × 65 control matrix) from user preferences and clinical templates, ensuring deterministic safety and predictable outcomes.

Interactive AI – “SENSAI”

A conversational agent that speaks with the user before, during and after sessions. Sentiment and intent signals feed back into the adaptive layer for more personalised regulation.

Adaptive AI

A multimodal Transformer-lite model (≤ 15M parameters) fuses EEG, HRV, GSR, facial expression and voice prosody to adjust light, sound, airflow, temperature and scent within safe, validated ranges.

Generative AI

A conditional variational auto-encoder introduces subtle variations in sensory stimulation patterns to prevent habituation.

WORK PLAN (24 MONTHS)

From Prototype to Certified Medical Device

Work Packages & Milestones

WP1 – Static & Interactive AI (Months 0–4)

Finalise deterministic session planning and conversational layer, and start the CE technical file. Target TRL: 6.

WP2 – Multimodal Classifier (Months 3–9)

Train multimodal emotion classifier on ≥ 2,000 in-pod sessions covering EEG, HRV, GSR, facial and voice signals. Target TRL: 6.

WP3 – Adaptive Closed Loop (Months 6–12)

Implement and validate ≤ 800 ms closed-loop Adaptive AI with a go/no-go gate for full deployment. Target TRL: 7.

WP4 – Clinical Pilot (Months 9–18)

Run a registered clinical pilot (n ≥ 120, 3 sites) to evaluate safety and efficacy in real-world settings. Target TRL: 7–8.

WP5 – Certification (Months 12–20)

Complete CE-marking as a Class IIa medical device and GDPR Data Protection Impact Assessment. Target TRL: 8.

WP6 – Commercial Launch (Months 18–24)

Launch the full pod solution and a VR-only light edition for broader deployment. Target TRL: 9.

OPEN INNOVATION & RESPONSIBLE AI

Sharing Data, Tools and Governance

Open Science Commitments

Upon project completion, Sensiks will release an anonymised multimodal dataset (≥ 5,000 labelled sessions), pre-trained emotion recognition models on Hugging Face under a research-friendly licence, and an open Python SDK and API so researchers and content creators can build on the platform.

Responsible AI & Ethics

  • Independent AI Ethics Officer overseeing bias audits, Model Cards and uncertainty reporting.
  • Strict safety constraints on all actuator changes to avoid overstimulation or adverse events.
  • Privacy by design with GDPR compliance and a full DPIA for handling biosensor data.
  • Human-in-the-loop workflows ensuring clinicians remain in control of therapeutic decisions.
NECESSITY OF SUBSIDY

Why MIT R&D AI Support is Critical

Scaling from Prototype to Certified Platform

Sensiks has self-funded more than €2.5 million of development. The MIT R&D AI subsidy will de-risk the final steps from functional prototype to certified, scalable medical device and open platform.

Accelerate Adaptive AI

Complete the Adaptive AI layer and multimodal classifier with robust validation across real-world users and settings.

Clinical Validation

Fund the registered clinical pilot (n ≥ 120), including recruitment, monitoring and longitudinal follow-up.

Certification & Ecosystem

Achieve CE Class IIa certification and deliver the open dataset, models and SDK that maximise public benefit and research reuse.

STATE SHIFTER™ as a Flagship for Responsible AI in Health

STATE SHIFTER™ / SENSAI combines clinically grounded protocols, multisensory hardware and adaptive AI to create a new class of digital therapeutic for stress, anxiety and trauma-related complaints. With MIT R&D AI support, it can become a certified, open, and widely accessible platform that benefits patients, workers and researchers across the Netherlands and beyond.